Favier, Benoit

Models available:

  • Primary human neutrophils and dendritic cells.
  • Non-human primate (NHP) models of human  infectious diseases.

Cells available:

  • Dendritic cells and Neutrophils

Technology available:

  • Flow cytometry and  CyTOF for multiparameter cell analysis
  • Luminex
  • RNAseq
  • Confocal microcopy

Key publications related to Mye-EUNITER:

  1. Baudhuin J., Migraine J., Faivre V., Loumagne L., Lukaszewicz AC, Payen D., Favier B. Exocytosis acts as a modulator of the ILT4 mediated inhibition of neutrophil functions  PNAS 2013. 110:17957-62

  2. Baudhuin J, Lesport E, Sousa S, Migraine J, Vigneron J, Lemaoult J, Carosella ED, Mooney N, Favier B. HLA-G inhibition of NK-cell cytolytic function is uncoupled from tumour cell lipid raft reorganization.  Eur J Immunol. 2012. 42:700-9

  3. Taflin C., Favier B., Baudhuin J., Savenay A., Hemon P., Bensussan A., Charron D., Glotz D., Mooney N. Human endothelial cells generate Th17 and regulatory T cells under inflammatory conditions. PNAS. 2011. 108:2891-6

  4. Lesport E., Baudhuin J., Sousa S., Lemaoult J., Zamborlini A., Rouas-Freiss N., Carosella ED., Favier B. Inhibition of human Vg9Vd2 T cell anti-tumoral activity through HLA-G: implications for immunotherapy of cancer. Cell Mol Life Sci. 2011. 68:3385-99

  5. Favier B., Lemaoult J, Lesport E, Carosella ED. ILT2/HLA-G interaction impairs NK-cell functions through the inhibition of the late but not the early events of the NK-cell activating synapse. FASEB J. 2010. 24:689-99