Mye-EUNITER
 

Jablonska, Jadwiga

Research interests focus on tumor models in mice (solid, AML), inflammation and neutrophils, interferon mediated neutrophil polarization, as well as bacterial infections and neutrophil activation.

Models available:

See above.

Cells available:

Neutrophils.

Technology available:

Flow cytometry, immunofluorescence and confocal microscopy, molecular biology techniques.

Key publications related to Mye-EUNITER:

  1. Jablonska, J., S. Leschner, K. Westphal, S. Lienenklaus, and S. Weiss. 2010. Neutrophils responsive to endogenous IFN-beta regulate tumor angiogenesis and growth in a mouse tumor model. J Clin Invest 120:1151-1164.
  2. Jablonska, J., C.F. Wu, L. Andzinski, S. Leschner, and S. Weiss. 2013. CXCR2-mediated tumor associated neutrophil recruitment is regulated by IFN-beta. Int.J Cancer. 2014 Mar 15;134(6):1346-58.
  3. Andzinski, L., C.F. Wu, S. Lienenklaus, A. Kroger, S. Weiss, and J. Jablonska. 2014. Delayed apoptosis of tumor associated neutrophils in the absence of endogenous IFN-beta. Int.J Cancer.136: 572–583.
  4. Wu, C.-F., Andzinski, L., Kasnitz, N., Kröger, A., Klawonn, F., Lienenklaus, S., Weiss, S. and Jablonska, J. (2015), The lack of type I interferon induces neutrophil-mediated pre-metastatic niche formation in the mouse lung. Int. J. Cancer, 137: 837–847.
  5. Andzinski, L., Kasnitz, N., Stahnke, S., Wu, C.-F., Gereke, M., von Köckritz-Blickwede, M., Schilling, B., Brandau, S., Weiss, S. and Jablonska, J. (2016), Type I IFNs induce anti-tumor polarization of tumor associated neutrophils in mice and human. Int. J. Cancer, 138: 1982–1993.

Contact details:

Department of Otorhinolaryngology
Research Division
Universitätsklinikum Essen
University of Duisburg-Essen
Hufelandstrasse 55
45122 Essen
Germany
Tel.: +49 201 / 723-3191
Fax: +49 201 / 723-5196
E-Mail: jja@gbf.de