Marcinkiewicz, Janusz

Models available:

  • Mouse models to study arthritis (CIA), colitis and contact sensitivity reaction

Cells available:

  • Neutrophils
  • Macrophages
  • Dendritic cells
  • In vitro and in vivo model to study effects of neutrophil-derived oxidants on antigen immunogenecity.
  • Experimental model of bacterial biofilm formation.
  • Model for functional macrophage polarization after contact with MPO-halide system products and bacterial biofilm matrix components.

Technology available:

  • Flow cytometry (up to 4-color)
  • Cellular immunology
  • Immunohistochemistry, 
  • Exosomes separation and functional analysis

Key publications related to Mye-EUNITER:

  1. Józefowski S, Biedroń R, Sróttek M, Chadzińska M, Marcinkiewicz J. The class A scavenger receptor SR-A/CD204 and the class B scavenger receptor CD36 regulate immune functions of macrophages differently Innate Immun. 2014 Nov;20(8):826-47.

  2. A.Pastuła, J.Marcinkiewicz. Myeloid-derived suppressor cells: a double-edged sword? International Journal of Experimental Pathology.2011

  3. J. Marcinkiewicz, A.Wojas-Pelc, M.Walczewska, S.Lipko-Godlewska, R.Jachowicz, A.Maciejewska, A.Białecka, A.Kasprowicz.Topical taurine bromamine, anew candidate in the treatment of moderate inflammatory acne vulgaris – A pilot study. European Journal of Dermatology 2008; 18(4) ; (433-439)

  4. R.Olszanecki, J.Marcinkiewicz Taurine chloramine and taurine bromamine induce heme oxygenase – 1 in resting and LPS – stimulated J774.2 macrophages. Amino Acids 2004; 27: (29-35) 

  5. J.Marcinkiewicz. Neutrophil chloramines: missing links between innate and acquired immunity. Immunol Today 1997, 18, 577-581.