Münz, Christian

Models available:

Human immune responses, autophagy, antigen processing, mice with reconstituted human immune system components

Cells available:

  • Natural Killer (NK) cells, dendritic cells, 

Technology available:

Model of human immune system component reconstitution in mice (an in vivo model of the human immune system).

Key publications related to Mye-EUNITER:

  1. Till Strowig*, Obinna Chijioke*, Paolo Carrega, Frida Arrey, Sonja Meixlsperger, Patrick C. Rämer, Guido Ferlazzo* and Christian Münz*. Human NK cells of mice with reconstituted human immune system components require pre-activation to acquire functional competence. Blood (2010), 116(20):4158-4167

  2. Rosa Barreira da Silva, Claudine Graf and Christian Münz. Cytoskeletal stabilization of inhibitory interactions between dendritic and natural killer cells. Blood (2011), 118(25): 6487-6498.

  3. Robert E. White*, Patrick C. Rämer*, Kikkeri N. Naresh, Sonja Meixlsperger, Laurie Pinaud, Cliona Rooney, Barbara Savoldo, Christian Münz* and Martin J. Allday*. EBNA3B-deficient Epstein-Barr virus induces aggressive B cell lymphoma lacking infiltrating T cells. Journal of Clinical Investigation (2012), 122(4):1487-502.

  4. Sonja Meixlsperger, Carol S. Leung, Patrick C. Rämer, Maggi Pack, Liliana D. Vanoaica, Gaelle Breton, Steve Pascolo, Andres M. Salazar, Andrzej Dzionek, Jürgen Schmitz, Ralph M. Steinman and Christian Münz, “CD141+ dendritic cells produce prominent amounts of IFN- after dsRNA recognition and can be targeted via DEC-205 in humanized mice”, Blood (2013),121:5034-5044.

  5. Obinna Chijioke, Anne Müller, Regina Feederle, Mario Henrique M. Barros, Carsten Krieg, Vanessa Emmel, Emanuela Marcenaro, Carol S. Leung, Olga Antsiferova, Vanessa Landtwing, Walter Bossart, Alessandro Moretta, Rocio Hassan, Onur Boyman, Gerald Niedobitek, Henri-Jacques Delecluse, Riccarda Capaul and Christian Münz, “Natural killer cells prevent infectious mononucleosis features”, Cell Reports (2013), 5(6):1489-98.