Mye-EUNITER
 

Ochando, Jordi

My laboratory investigates the role of myeloid suppressive cells in experimental mice models of transplantation.

Models available:

Experimental mice models of transplantation

Cells available:

MDSC and Macrophages

Technology available:

Flow and Mass cytometry. Microsurgery for heart transplantation in mice.

Key publications related to Mye-EUNITER:

  1. Ginhoux F, Schultze JL, Murray PJ, Ochando J, Biswas SK. 2015. New insights into the multidimensional concept of macrophage ontogeny, activation and function. Nat Immunol. 17(1):34-40. doi: 10.1038/ni.3324. PMID: 26681460
  2. Ochando J, Kwan WH, Ginhoux F, Hutchinson JA, Hashimoto D, Collin M. 2015. The mononuclear phagocyte system in organ transplantation. Am J Transplant. doi: 10.1111/ajt.13627. PMID: 26602545
  3. Ochando J, Conde P, Bronte V. 2015. Monocyte-Derived Suppressor Cells in Transplantation. Curr Transplant Rep. 2015;2(2):176-183. PMID: 26301174
  4. Conde P, Rodriguez M, van der Touw W, Jimenez A, Burns M, Miller J, Brahmachary M, Chen HM, Boros P, Rausell-Palamos F, Yun TJ, Riquelme P, Rastrojo A, Aguado B, Stein-Streilein J, Tanaka M, Zhou L, Zhang J, Lowary TL, Ginhoux F, Park CG, Cheong C, Brody J, Turley SJ, Lira SA, Bronte V, Gordon S, Heeger PS, Merad M, Hutchinson J, Chen SH, Ochando J. 2015. DC-SIGN(+) Macrophages Control the Induction of Transplantation Tolerance. Immunity. 16;42(6):1143-58. PMID: 26070485
  5. Garcia MR, Ledgerwood L, Yang Y, Xu J, Lal G, Burrell B, Ma G, Hashimoto D, Li Y, Boros P, Grisotto M, van Rooijen N, Matesanz R, Tacke F, Ginhoux F, Ding Y, Chen SH, Randolph G, Merad M, Bromberg JS, and Ochando JC. 2010. Monocytic suppressive cells mediate cardiovascular transplantation tolerance in mice. J Clin Invest 120:2486-2496, PMID:20551515, PMCID:PMC2898596

Contact details:

Head of the Transplant Immunology Laboratory
Instituto de Salud Carlos III
Av. de Monforte de Lemos, 5
28029 Madrid
Spain
Tel. +34-91822 3274
jochando@isciii.es